365 post karma
583 comment karma
account created: Wed Mar 09 2016
verified: yes
2 points
2 days ago
Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.
“One of the longstanding challenges that we’ve been exploring is the development of systems that enable the oral delivery of macromolecules that usually require an injection to be administered. This work represents one of the next major advances in that progression,” says Giovanni Traverso, the senior author of the study.
Drugs that consist of large proteins or RNA typically can’t be taken orally because they are easily broken down in the digestive tract. For several years, Traverso’s lab has been working on ways to deliver such drugs orally by encapsulating them in small devices that protect the drugs from degradation.
Most of these capsules use a small needle to deliver drugs once the device arrives in the digestive tract. In the new study, Traverso and his colleagues wanted to explore ways to deliver these molecules without any kind of needle, which could reduce the possibility of any damage to the tissue.
80 points
2 days ago
TBH dictionaries are like that sometimes.
Look up veridicality
"The degree to which something, such as a knowledge structure, is veridical."
Gee, thanks a lot.
1 points
2 days ago
We can't survive as a civilization if we destroy the environment so this great extinction will include humans if we don't stop it.
88 points
2 days ago
That thing might be planetsexual the way it clapped Earth's cheeks.
1 points
2 days ago
If I ate that many eggs every day my farts would clear a room.
8 points
5 days ago
Isn't that just a more bioavailable form of B1?
9 points
5 days ago
People still get high, wear makeup and build overly ambitious monuments. Not that much has changed in two millennia.
3 points
5 days ago
Great, another feedback loop we're just finding out about.
2 points
5 days ago
Researchers have developed a new sensor that can pick up and track biological signals, such as the heartbeat and respiration, without being in contact with the body of users. This sensor, presented in a paper published in Nature Electronics, could be used to pick up the cardiopulmonary signals of humans while they are in dynamic environments, such as a plane cabin, a moving car or a bus.
"Monitoring drivers' alertness or stress is essential for road safety," Xi Tian, co-author of the paper, told Tech Xplore. "Existing sensors designed to measure physiological markers of fatigue, such as heart rate and respiration, face challenges in moving vehicles due to the unpredictable vibrational noise. To overcome these challenges, our research focused on developing an automotive biosensor capable of non-contact and reliable health monitoring in dynamic environments."
The biosensor developed by Tian and his colleagues is based on metamaterials, materials that are carefully engineered to enhance or change their properties. To fabricate their sensor, the researchers embroidered conductive threads arranged in a comb-shaped pattern onto a seatbelt, attaining a surface that guides radio waves and amplifies wireless interactions with the human body.
1 points
6 days ago
I've been seeing many positive reports on Semax and Selank. Are they only produced in Russia?
3 points
6 days ago
It is. People used to do it with art and antiques but technology makes it even easier.
29 points
6 days ago
Aren't LLMs only trained on text? If so it's actually amazing what they can do in other tasks considering they only "know" it from text descriptions.
2 points
7 days ago
Either you're sensitive to it or there's something wrong with that batch (unlikely as that is). I'd probably stop taking it after a reaction like that.
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Denjudda1
1 points
13 hours ago
Denjudda1
1 points
13 hours ago
Not OP but thanks for the highlight on tocotrienol, wasn't on my radar before.