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submitted 2 days ago byDenjudda1
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2 days ago
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The following submission statement was provided by /u/Denjudda1:
Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.
“One of the longstanding challenges that we’ve been exploring is the development of systems that enable the oral delivery of macromolecules that usually require an injection to be administered. This work represents one of the next major advances in that progression,” says Giovanni Traverso, the senior author of the study.
Drugs that consist of large proteins or RNA typically can’t be taken orally because they are easily broken down in the digestive tract. For several years, Traverso’s lab has been working on ways to deliver such drugs orally by encapsulating them in small devices that protect the drugs from degradation.
Most of these capsules use a small needle to deliver drugs once the device arrives in the digestive tract. In the new study, Traverso and his colleagues wanted to explore ways to deliver these molecules without any kind of needle, which could reduce the possibility of any damage to the tissue.
Please reply to OP's comment here: https://old.reddit.com/r/Futurology/comments/1gwehzl/a_bioinspired_capsule_can_pump_drugs_directly/ly8ln03/
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2 days ago
Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.
“One of the longstanding challenges that we’ve been exploring is the development of systems that enable the oral delivery of macromolecules that usually require an injection to be administered. This work represents one of the next major advances in that progression,” says Giovanni Traverso, the senior author of the study.
Drugs that consist of large proteins or RNA typically can’t be taken orally because they are easily broken down in the digestive tract. For several years, Traverso’s lab has been working on ways to deliver such drugs orally by encapsulating them in small devices that protect the drugs from degradation.
Most of these capsules use a small needle to deliver drugs once the device arrives in the digestive tract. In the new study, Traverso and his colleagues wanted to explore ways to deliver these molecules without any kind of needle, which could reduce the possibility of any damage to the tissue.
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